ZNF518A

Across TCGA patient cohorts, ZNF518A mutation is significantly associated with the total protein of many other genes, with 67 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF518A-associated genes across cancer lineages are p21, ATM, and INPP4B. Each is linked with ZNF518A in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF518A-to-partner and partner-to-ZNF518A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, p21 grouped by ZNF518A-low versus ZNF518A-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF518A→partner) and Y-score (partner→ZNF518A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	p21 →	+0.579	+2.999	.009	.035	3	3
COAD	ATM →	-0.661	-2.450	<.001	.020	3	3
UCEC	INPP4B →	-0.338	-1.723	<.001	<.001	3	2
UCEC	MEK1 →	+0.497	+2.765	<.001	<.001	3	2
UCEC	PARP_cleaved →	-0.198	-2.070	.025	.001	3	2
COAD	Rad50 →	-0.378	-3.169	<.001	.017	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 67 associations by consensus.

p21 by ZNF518A expression — BLCA

Explore this box plot interactively →