ZNF518A

Across TCGA cell cohorts, ZNF518A RNA expression is significantly associated with the go_rna of many other GO terms, with 4,556 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ZNF518A-associated GO terms across cancer lineages are Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway, Regulation of mRNA catabolic process, and Positive regulation of DNA metabolic process. Each is linked with ZNF518A in more than 16 cancer types. Because this analysis shows association rather than direction, both ZNF518A-to-partner and partner-to-ZNF518A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway grouped by ZNF518A-low versus ZNF518A-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF518A→partner) and Y-score (partner→ZNF518A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway →	+0.143	+1.126	.002	<.001	2	17
STOMACH	Regulation of mRNA catabolic process →	+0.051	+1.374	.004	.001	3	16
BONE	Positive regulation of DNA metabolic process →	+0.106	+1.145	<.001	<.001	3	15
LUNG_NSCLC_LUSC	Vesicle tethering →	+0.084	+0.865	.001	.009	2	16
BLOOD_Lymphoma	Positive regulation of mRNA metabolic process →	+0.050	+0.613	<.001	.003	3	14
BONE	Heterochromatin formation →	+0.093	+0.889	<.001	.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,556 associations by consensus.

Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway by ZNF518A expression — BONE

Explore this box plot interactively →