Across TCGA patient cohorts, ZNF517 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,563 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNF517-associated proteins across cancer lineages are SCRIB, C8orf82, and MAN2A1. Each is linked with ZNF517 in more than 7 cancer types. Because this analysis shows association rather than direction, both ZNF517-to-partner and partner-to-ZNF517 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF517→partner) and Y-score (partner→ZNF517) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SCRIB →	+0.493	+1.006	<.001	<.001	3	8
OV	C8orf82 →	+0.949	+1.009	<.001	<.001	3	7
GBM	MAN2A1 →	-0.448	-0.338	<.001	<.001	3	7
LSCC	WDR5 →	+0.186	+0.483	<.001	<.001	3	6
COAD	BRD3 →	+0.287	+0.423	.004	.005	3	6
GBM	UNC13D →	-0.436	-0.323	.002	.004	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,563 associations by consensus.

Exploration

ZNF517 survival (RNA) · tumor vs normal (RNA) · all ZNF517 data types