ZNF517

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZNF517 mutation is significantly associated with the RNA expression of many other genes, with 1,393 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF517-associated genes across cancer lineages are MOCS1P1, NF1P10, and SNORD113-4. Each is linked with ZNF517 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF517-to-partner and partner-to-ZNF517 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF517→partner) and Y-score (partner→ZNF517) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCMOCS1P1 →+0.033+3.816.005.00732
CESCNF1P10 →+0.161+6.154<.001<.00132
COADSNORD113-4 →+0.727+3.541<.001.00732
READRNU6-800P →+0.466+5.039<.001.00832
READDNAJB6P5 →+0.077+5.219<.001.00632
READNAGPA-AS1 →+0.117+5.421<.001.00532
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,393 associations by consensus.

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