Across TCGA cell cohorts, ZNF517 mutation is significantly associated with the mutation status of many other genes, with 4,900 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF517-associated genes across cancer lineages are TEAD2, STXBP2, and CCDC33. Each is linked with ZNF517 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF517-to-partner and partner-to-ZNF517 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF517→partner) and Y-score (partner→ZNF517) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	TEAD2 →	+3.341	+3.341	.001	.001	1	4
BLOOD_Leukemia	STXBP2 →	+4.247	+3.560	.002	.002	1	4
BREAST	CCDC33 →	+5.297	+5.297	.004	.004	1	4
BREAST	SOGA1 →	+4.297	+4.857	.009	.009	1	4
BREAST	ZDHHC5 →	+4.297	+4.857	.009	.009	1	4
BREAST	THAP4 →	+5.297	+5.297	.004	.004	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,900 associations by consensus.

Exploration

ZNF517 survival (RNA) · tumor vs normal (RNA) · all ZNF517 data types