ZNF516-DT

Across TCGA patient cohorts, ZNF516-DT RNA expression is significantly associated with the protein abundance of many other proteins, with 8,526 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ZNF516-DT-associated proteins across cancer lineages are ZNF516, ZNF516_S116, and NUFIP2. Each is linked with ZNF516-DT in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF516-DT-to-partner and partner-to-ZNF516-DT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF516-DT versus ZNF516 in BRCA, with a Pearson correlation of 0.63.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF516-DT→partner) and Y-score (partner→ZNF516-DT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ZNF516 →	+0.655	+0.544	<.001	<.001	3	4
LSCC	ZNF516_S116 →	+0.766	+0.298	<.001	<.001	3	3
COAD	NUFIP2 →	+0.315	+0.250	<.001	<.001	3	3
COAD	NARS1 →	+0.233	+0.164	<.001	<.001	3	3
LUAD	ME1 →	+0.490	+0.272	<.001	<.001	3	3
UCEC	PDXK →	-0.300	-0.405	.007	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,526 associations by consensus.

ZNF516-DT vs ZNF516 — BRCA

Explore this scatter interactively →