ZNF487

Across TCGA patient cohorts, ZNF487 mutation is significantly associated with the RNA expression of many other genes, with 621 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF487-associated genes across cancer lineages are SNORD115-22, MIR206, and PABPC1L2B-AS1. Each is linked with ZNF487 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF487-to-partner and partner-to-ZNF487 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNORD115-22 grouped by ZNF487-low versus ZNF487-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF487→partner) and Y-score (partner→ZNF487) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	SNORD115-22 →	+0.383	+7.816	<.001	.008	3	1
SKCM	MIR206 →	+0.262	+7.816	<.001	.008	3	1
SKCM	PABPC1L2B-AS1 →	+0.034	+7.816	<.001	.008	3	1
UCEC	RN7SL713P →	+0.095	+3.279	.006	.006	3	1
UCEC	RN7SL605P →	+0.368	+3.150	.007	.001	3	1
UCEC	MIR5091 →	+0.525	+2.315	.005	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 621 associations by consensus.

SNORD115-22 by ZNF487 expression — SKCM

Explore this box plot interactively →