ZNF436

Across TCGA patient cohorts, ZNF436 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,976 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ZNF436-associated proteins across cancer lineages are MYL6, ITGAV, and LUZP1. Each is linked with ZNF436 in more than 5 cancer types. Because this analysis shows association rather than direction, both ZNF436-to-partner and partner-to-ZNF436 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF436 versus MYL6 in PDAC, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF436→partner) and Y-score (partner→ZNF436) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	MYL6 →	+0.427	+0.411	.001	.002	3	6
OV	ITGAV →	+0.584	+0.586	<.001	<.001	3	5
OV	LUZP1 →	+0.304	+0.530	<.001	<.001	3	5
COAD	MRPL1 →	-0.350	-0.508	<.001	<.001	3	5
COAD	MRPS2 →	-0.318	-0.441	<.001	<.001	3	5
BRCA	MRPS27 →	-0.301	-0.655	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,976 associations by consensus.

ZNF436 vs MYL6 — PDAC

Explore this scatter interactively →