Across TCGA patient cohorts, ZNF431 protein abundance is significantly associated with the RNA expression of many other genes, with 88 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNF431-associated genes across cancer lineages are HNRNPA1P62, SLC32A1, and SEM1. Each is linked with ZNF431 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF431-to-partner and partner-to-ZNF431 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF431→partner) and Y-score (partner→ZNF431) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	HNRNPA1P62 →	+0.200	+1.292	<.001	.003	3	1
LSCC	SLC32A1 →	+0.053	+1.128	.001	.006	3	1
LSCC	SEM1 →	+1.200	+0.991	.007	.006	3	1
LSCC	BARX1 →	+2.576	+0.976	.007	.006	3	1
LSCC	BCAR3 →	-1.091	-1.108	.003	<.001	3	1
LSCC	SUSD4 →	+1.805	+1.108	.002	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 88 associations by consensus.

Exploration

ZNF431 survival (RNA) · tumor vs normal (RNA) · all ZNF431 data types