Across TCGA patient cohorts, ZNF431 mutation is significantly associated with the RNA expression of many other genes, with 3,063 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF431-associated genes across cancer lineages are RNU6-650P, RNU6-425P, and MIR875. Each is linked with ZNF431 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF431-to-partner and partner-to-ZNF431 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF431→partner) and Y-score (partner→ZNF431) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU6-650P →	+0.297	+3.807	<.001	.001	3	3
BLCA	RNU6-425P →	+0.312	+4.588	<.001	.008	3	3
SKCM	MIR875 →	+0.203	+4.199	.001	.009	3	3
BLCA	RN7SL318P →	+0.198	+4.840	.001	.002	3	3
LIHC	CDRT15P7 →	+0.091	+6.129	<.001	<.001	3	3
BRCA	MIR548AY →	+0.425	+4.658	.002	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,063 associations by consensus.

Exploration

ZNF431 survival (RNA) · tumor vs normal (RNA) · all ZNF431 data types