ZNF382

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZNF382 mutation is significantly associated with the RNA expression of many other genes, with 2,308 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF382-associated genes across cancer lineages are RNU6-1207P, RN7SKP252, and GLRX5. Each is linked with ZNF382 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF382-to-partner and partner-to-ZNF382 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1207P grouped by ZNF382-low versus ZNF382-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF382→partner) and Y-score (partner→ZNF382) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCRNU6-1207P →+0.296+4.669<.001.00733
LUADRN7SKP252 →+0.144+3.938<.001.00933
UCECGLRX5 →+0.319+2.617.006<.00133
UCECUPP1 →+0.561+3.385.001.00433
UCECTMX2 →+0.432+1.885.001.00133
SKCMATP6V1D →+0.597+3.629<.001.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,308 associations by consensus.

RNU6-1207P by ZNF382 expression — CESC

Box plot of RNU6-1207P in ZNF382-low vs ZNF382-high samples in CESC.

Explore this box plot interactively →

Exploration