ZNF346-IT1

Across TCGA patient cohorts, ZNF346-IT1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,469 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF346-IT1-associated proteins across cancer lineages are BUB3, SIN3B, and PNN. Each is linked with ZNF346-IT1 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZNF346-IT1-to-partner and partner-to-ZNF346-IT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF346-IT1 versus BUB3 in LSCC, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF346-IT1→partner) and Y-score (partner→ZNF346-IT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	BUB3 →	+0.359	+0.659	<.001	<.001	3	5
HNSC	SIN3B →	+0.262	+0.688	<.001	.004	3	4
GBM	PNN →	+0.352	+0.630	<.001	<.001	3	4
LSCC	PRAM1_S298 →	-1.118	-0.553	<.001	<.001	3	4
LSCC	ARID4B →	+0.287	+0.440	<.001	.002	3	4
LSCC	RBM22 →	+0.231	+0.573	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,469 associations by consensus.

ZNF346-IT1 vs BUB3 — LSCC

Explore this scatter interactively →