ZNF333

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ZNF333 mutation is significantly associated with the RNA expression of many other genes, with 38 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF333-associated genes across cancer lineages are PYURF, CPLX4, and OR2C1. Each is linked with ZNF333 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF333-to-partner and partner-to-ZNF333 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PYURF grouped by ZNF333-low versus ZNF333-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF333→partner) and Y-score (partner→ZNF333) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEPYURF →+0.606+3.067<.001.00931
LARGE_INTESTINECPLX4 →+0.029+3.222<.001.00231
LARGE_INTESTINEOR2C1 →+0.105+3.047<.001.00531
LARGE_INTESTINETRAM1L1 →+0.961+3.067<.001.00931
LARGE_INTESTINEFAM153B →+0.412+2.648.001.00831
LARGE_INTESTINESATL1 →+0.125+3.614.005.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 38 associations by consensus.

PYURF by ZNF333 expression — LARGE_INTESTINE

Box plot of PYURF in ZNF333-low vs ZNF333-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration