ZNF333

Across TCGA pan-cancer cohorts, ZNF333 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of ZNF333’s most consistent transcriptional readouts.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where ZNF333 RNA is repressed in tumor relative to normal tissue. In most cancer types ZNF333 is over-expressed in tumor, although a few such as UCEC and THCA show the opposite, repressed pattern.

UCEC, THCA, and LIHC are the cancer types where ZNF333 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ZNF333 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
UCEC	All	IV	−1.550	<.001	8	view →
THCA	Male	II,III,IV	−0.712	<.001	8	view →
LIHC	Female	II,III,IV	+0.620	<.001	8	view →
LUAD	All	III,IV	−0.443	<.001	7	view →
KIRC	All	All	+0.259	<.001	7	view →
BRCA	All	III,IV	−0.514	<.001	6	view →
HNSC	All	III,IV	+0.302	.005	6	view →
CHOL	Male	All	+1.238	<.001	5	view →
KICH	Female	All	−0.662	<.001	5	view →
LUSC	All	All	−0.246	.004	5	view →
READ	All	III,IV	+0.109	.020	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

ZNF333–UCEC

Open the UCEC breakdown →