ZNF324

Across TCGA patient cohorts, ZNF324 mutation is significantly associated with the RNA expression of many other genes, with 2,290 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF324-associated genes across cancer lineages are SNORD30, UBE2V1P8, and ATF4P1. Each is linked with ZNF324 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF324-to-partner and partner-to-ZNF324 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNORD30 grouped by ZNF324-low versus ZNF324-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF324→partner) and Y-score (partner→ZNF324) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SNORD30 →	+0.695	+1.849	.008	.005	3	2
BLCA	UBE2V1P8 →	+0.206	+6.814	<.001	<.001	3	2
UCEC	ATF4P1 →	+0.044	+1.980	<.001	.006	3	2
BRCA	TP53TG3F →	+0.007	+7.473	<.001	.007	3	1
BRCA	RPL27AP4 →	+0.062	+4.540	.003	.009	3	1
BRCA	LINC02567 →	+0.198	+5.655	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,290 associations by consensus.

SNORD30 by ZNF324 expression — UCEC

Explore this box plot interactively →