Q-omics provides the consensus-scored RPL27AP4 profile across patient tissues and cancer cell-line models. RPL27AP4 expression is associated with patient survival in 10 of 34 cancer types, with the highest sampling consensus in ACC. Additionally, RPL27AP4 RNA expression shows 4,566 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight ACC, and STAD as cancer lineages where RPL27AP4 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Premium analyses for RPL27AP4 — synthetic lethality, tumor antigen, and pembrolizumab response.

View premium →

Survival associations

This table summarizes RPL27AP4 survival associations across molecular data types. RPL27AP4 RNA expression shows survival associations in the most cancer types (10). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

RPL27AP4 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	10	ACC (180)	view →

This table ranks reproducible RPL27AP4 RNA expression–survival associations across cancer types. High RPL27AP4 expression shows unfavorable associations in ACC, THCA, PAAD, LUAD, COAD and ESCA. The ACC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify ACC as the clearest survival context for RPL27AP4 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Tertile	All	0.324	0.834	<.001	180	view →
THCA	OS	Tertile	II,III,IV	0.925	0.981	<.001	72	view →
PAAD	OS	Tertile	II,III,IV	0.252	0.561	.004	36	view →
LUAD	OS	Tertile	III,IV	0.318	0.671	.040	36	view →
COAD	OS	Tertile	IV	0.047	0.679	<.001	36	view →
ESCA	OS	Tertile	All	0.598	0.895	.043	9	view →

Pink = unfavorable, green = favorable. all 10 lineages →

RPL27AP4-ACC (OS)

Kaplan–Meier survival curve for RPL27AP4 RNA expression in ACC: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with RPL27AP4 in patient tissues and cancer cell lines. In patient samples, RPL27AP4 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
Function (RNA)	4,566	STAD (4095)	view →
RNA	1,385	LUSC (252)	view →