ZNF30

Across TCGA cell cohorts, ZNF30 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF30-associated genes across cancer lineages are RBMY1A1, CLEC1B, and ADAM2. Each is linked with ZNF30 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF30-to-partner and partner-to-ZNF30 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RBMY1A1 grouped by ZNF30-low versus ZNF30-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF30→partner) and Y-score (partner→ZNF30) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	RBMY1A1 →	+0.143	+5.807	<.001	.001	3	1
LUNG_SCLC	CLEC1B →	+0.045	+5.029	<.001	.006	3	1
BLOOD_Leukemia	ADAM2 →	+0.105	+5.539	.001	.003	3	1
STOMACH	USP17L20 →	+0.014	+4.432	<.001	.003	3	1
STOMACH	USP17L18 →	+0.014	+4.129	<.001	.007	3	1
LARGE_INTESTINE	PRSS54 →	+0.034	+3.760	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

RBMY1A1 by ZNF30 expression — OVARY

Explore this box plot interactively →