ZNF30

Across TCGA pan-cancer cohorts, ZNF30 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated ZNF30 data layer compared with 3 for mutation status.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher ZNF30 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated ZNF30 expression acts as an unfavorable survival marker, although some lineages such as BRCA and READ show a favorable association.

BRCA, LGG, and READ are the cancer types where ZNF30 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	DFS	Tertile	II,III,IV	0.961	0.907	.004	51	view →
LGG	DFS	Median	All	0.650	0.825	<.001	51	view →
READ	OS	Median	All	0.968	0.849	.001	43	view →
PAAD	DFS	Median	All	0.361	0.175	.006	36	view →
LIHC	OS	Quartile	All	0.557	0.796	<.001	35	view →
ACC	DFS	Quartile	All	0.559	0.872	.005	32	view →
KICH	DFS	Median	III,IV	0.314	0.895	.001	29	view →
KIRP	DFS	Median	IV	0.038	0.527	.010	21	view →
GBM	DFS	Tertile	All	0.456	0.161	<.001	20	view →
SKCM	OS	Median	All	0.842	0.900	.005	19	view →
HNSC	OS	Tertile	All	0.609	0.839	.002	19	view →
CESC	DFS	Median	III,IV	0.567	0.850	.002	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

ZNF30–BRCA (DFS)

Open the BRCA breakdown →