ZNF287

Across TCGA cell cohorts, ZNF287 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF287-associated genes across cancer lineages are KRTAP12-1, KIR2DS4, and REG1B. Each is linked with ZNF287 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF287-to-partner and partner-to-ZNF287 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP12-1 grouped by ZNF287-low versus ZNF287-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF287→partner) and Y-score (partner→ZNF287) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	KRTAP12-1 →	+0.066	+4.807	<.001	.006	3	1
BLOOD_Myeloma	KIR2DS4 →	+0.023	+4.807	<.001	.006	3	1
LARGE_INTESTINE	REG1B →	+2.047	+3.196	.001	.007	3	1
LARGE_INTESTINE	OR4F4 →	+0.014	+3.688	.001	.002	3	1
LARGE_INTESTINE	TBC1D3 →	+0.061	+3.688	<.001	.002	3	1
BLOOD_Leukemia	ASZ1 →	+0.145	+4.152	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

KRTAP12-1 by ZNF287 expression — BLOOD_Myeloma

Explore this box plot interactively →