ZNF280D

Across TCGA cell cohorts, ZNF280D RNA expression is significantly associated with the go_rna of many other GO terms, with 2,610 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF280D-associated GO terms across cancer lineages are Positive regulation of cilium assembly, Regulation of maintenance of sister chromatid cohesion, and Regulation of maintenance of mitotic sister chromatid cohesion. Each is linked with ZNF280D in more than 12 cancer types. Because this analysis shows association rather than direction, both ZNF280D-to-partner and partner-to-ZNF280D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of cilium assembly grouped by ZNF280D-low versus ZNF280D-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF280D→partner) and Y-score (partner→ZNF280D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Positive regulation of cilium assembly →	+0.091	+1.016	<.001	<.001	3	13
OVARY	Regulation of maintenance of sister chromatid cohesion →	+0.071	+0.504	<.001	.008	3	12
OVARY	Regulation of maintenance of mitotic sister chromatid cohesion →	+0.071	+0.504	<.001	.008	3	12
LUNG_SCLC	Mitotic G2 DNA damage checkpoint signaling →	+0.066	+0.561	.004	.005	2	12
SKIN	Post-Golgi vesicle-mediated transport →	+0.053	+0.618	.001	.002	3	11
UPPER_AERODIGESTIVE_TRACT	Cilium or flagellum-dependent cell motility →	-0.098	-0.830	.006	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,610 associations by consensus.

Positive regulation of cilium assembly by ZNF280D expression — BREAST

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