ZNF280D

Across TCGA cell cohorts, ZNF280D mutation is significantly associated with the RNA expression of many other genes, with 41 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ZNF280D-associated genes across cancer lineages are OR8D2, SYT10, and CSTL1. Each is linked with ZNF280D in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF280D-to-partner and partner-to-ZNF280D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR8D2 grouped by ZNF280D-low versus ZNF280D-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF280D→partner) and Y-score (partner→ZNF280D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	OR8D2 →	+0.077	+4.867	<.001	.009	3	2
SKIN	SYT10 →	+0.283	+3.217	<.001	.006	3	2
BLOOD_Lymphoma	CSTL1 →	+0.549	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	PLCZ1 →	+0.169	+5.643	<.001	.002	3	1
BLOOD_Lymphoma	XAGE5 →	+0.713	+5.643	<.001	.002	3	1
BLOOD_Lymphoma	NPAP1 →	+0.050	+4.867	.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

OR8D2 by ZNF280D expression — BLOOD_Lymphoma

Explore this box plot interactively →