ZNF280C

Across TCGA patient cohorts, ZNF280C RNA expression is significantly associated with the protein abundance of many other proteins, with 21,635 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNF280C-associated proteins across cancer lineages are RPL26, PHF6, and THOC6. Each is linked with ZNF280C in more than 6 cancer types. Because this analysis shows association rather than direction, both ZNF280C-to-partner and partner-to-ZNF280C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF280C versus RPL26 in GBM, with a Pearson correlation of -0.66.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF280C→partner) and Y-score (partner→ZNF280C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RPL26 →	-0.725	-0.470	<.001	<.001	3	7
GBM	PHF6 →	+0.426	+0.444	<.001	<.001	3	6
GBM	THOC6 →	+0.242	+0.458	.005	<.001	3	6
GBM	TOP2A →	+0.783	+0.484	<.001	<.001	3	5
GBM	RBMX2 →	+0.322	+0.417	.001	.002	3	5
GBM	STAG2 →	+0.271	+0.447	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,635 associations by consensus.

ZNF280C vs RPL26 — GBM

Explore this scatter interactively →