Across TCGA patient cohorts, ZNF273 protein abundance is significantly associated with the RNA expression of many other genes, with 228 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ZNF273-associated genes across cancer lineages are GPR143, PYCARD, and VPS35L. Each is linked with ZNF273 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF273-to-partner and partner-to-ZNF273 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF273→partner) and Y-score (partner→ZNF273) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	GPR143 →	-2.620	-1.329	.007	.001	3	1
BRCA	PYCARD →	-2.749	-1.046	.002	.001	3	1
BRCA	VPS35L →	-0.554	-0.960	.007	.004	3	1
BRCA	AURKC →	+0.537	+0.920	.007	.008	3	1
BRCA	CCDC114 →	-1.533	-1.246	.007	.007	3	1
BRCA	MRPS27 →	-0.593	-0.960	.003	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 228 associations by consensus.

Exploration

ZNF273 survival (RNA) · tumor vs normal (RNA) · all ZNF273 data types