ZNF256

Across TCGA patient cohorts, ZNF256 mutation is significantly associated with the RNA expression of many other genes, with 2,494 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF256-associated genes across cancer lineages are LINC01519, CGRRF1, and VAPA. Each is linked with ZNF256 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF256-to-partner and partner-to-ZNF256 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01519 grouped by ZNF256-low versus ZNF256-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF256→partner) and Y-score (partner→ZNF256) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	LINC01519 →	+0.033	+5.033	<.001	.009	3	2
COAD	CGRRF1 →	+0.654	+3.223	<.001	.008	3	2
COAD	VAPA →	+0.611	+3.472	<.001	.002	3	2
COAD	DHRS12 →	-0.579	-3.378	.002	.005	3	2
UCEC	NKG7 →	+1.158	+3.700	<.001	.001	3	2
COAD	MICU1 →	+0.393	+3.183	.002	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,494 associations by consensus.

LINC01519 by ZNF256 expression — LIHC

Explore this box plot interactively →