ZNF25

Across TCGA patient cohorts, ZNF25 mutation is significantly associated with the RNA expression of many other genes, with 1,359 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF25-associated genes across cancer lineages are RNA5SP419, RNA5SP414, and MIR8082. Each is linked with ZNF25 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF25-to-partner and partner-to-ZNF25 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP419 grouped by ZNF25-low versus ZNF25-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF25→partner) and Y-score (partner→ZNF25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RNA5SP419 →	+0.784	+4.102	<.001	.007	3	3
LUSC	RNA5SP414 →	+0.447	+4.102	<.001	.007	3	2
UCEC	MIR8082 →	+0.299	+1.976	<.001	.007	3	2
UCEC	RNA5SP412 →	+0.418	+1.967	.002	.002	3	2
COAD	CYCSP49 →	+0.243	+6.142	<.001	<.001	3	2
BLCA	OR5BB1P →	+0.065	+5.455	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,359 associations by consensus.

RNA5SP419 by ZNF25 expression — LUSC

Explore this box plot interactively →