ZNF212

Across TCGA patient cohorts, ZNF212 mutation is significantly associated with the total protein of many other genes, with 29 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF212-associated genes across cancer lineages are MEK1, PEA-15_pS116, and eEF2. Each is linked with ZNF212 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF212-to-partner and partner-to-ZNF212 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MEK1 grouped by ZNF212-low versus ZNF212-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF212→partner) and Y-score (partner→ZNF212) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MEK1 →	+0.548	+3.584	<.001	.002	3	2
UCEC	PEA-15_pS116 →	+0.464	+2.115	.002	.019	3	2
UCEC	eEF2 →	+0.404	+2.115	.009	.019	2	2
UCEC	EGFR_pY1068 →	-0.275	-3.459	.012	.005	3	1
UCEC	eIF4G →	+0.339	+3.169	.012	.018	3	1
UCEC	ERK2 →	+0.347	+3.584	<.001	.002	2	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

MEK1 by ZNF212 expression — UCEC

Explore this box plot interactively →