ZNF212

Across TCGA pan-cancer cohorts, ZNF212 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated ZNF212 data layer compared with 2 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher ZNF212 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ZNF212 expression acts as an unfavorable survival marker, although some lineages such as SCLC and BRCA show a favorable association.

COAD, ACC, and SCLC are the cancer types where ZNF212 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	II,III,IV	0.394	0.565	<.001	74	view →
ACC	DFS	Tertile	All	0.226	0.741	<.001	71	view →
SCLC	DFS	Median	II,III,IV	0.659	0.256	<.001	63	view →
BRCA	OS	Tertile	IV	0.772	0.127	.002	52	view →
THYM	DFS	Median	All	0.883	0.605	.001	36	view →
LGG	DFS	Median	All	0.677	0.797	<.001	32	view →
ESCA	OS	Median	III,IV	0.573	0.304	.004	31	view →
HNSC	OS	Quartile	All	0.824	0.701	.003	29	view →
KIRC	DFS	Median	II,III,IV	0.634	0.785	.009	28	view →
MESO	OS	Median	All	0.460	0.632	.007	25	view →
LIHC	DFS	Quartile	All	0.336	0.508	.002	23	view →
LUSC	DFS	Median	III,IV	0.473	0.921	.002	22	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

ZNF212–COAD (DFS)

Open the COAD breakdown →