ZNF212

Across TCGA pan-cancer cohorts, ZNF212 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of ZNF212’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where ZNF212 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ZNF212 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

HNSC, LIHC, and LUAD are the cancer types where ZNF212 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ZNF212 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	IV	+0.547	<.001	12	view →
LIHC	Female	III,IV	+0.992	<.001	9	view →
LUAD	All	III,IV	+0.673	<.001	9	view →
THCA	Male	III,IV	−0.491	<.001	9	view →
BLCA	All	All	+0.602	.001	8	view →
COAD	Male	II,III,IV	+0.381	<.001	8	view →
LUSC	Male	II,III,IV	+0.945	<.001	7	view →
KIRP	All	IV	+0.877	.002	6	view →
CHOL	Male	All	+1.903	<.001	5	view →
KIRC	All	All	+0.212	<.001	4	view →
KICH	All	All	−0.471	.002	2	view →
ESCA	Female	All	+0.549	.029	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

ZNF212–HNSC

Open the HNSC breakdown →