ZNF212

Across TCGA cell cohorts, ZNF212 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible ZNF212-associated genes across cancer lineages are MAGEB4, C7orf77, and FAM25C. Each is linked with ZNF212 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF212-to-partner and partner-to-ZNF212 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MAGEB4 grouped by ZNF212-low versus ZNF212-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF212→partner) and Y-score (partner→ZNF212) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	MAGEB4 →	+0.010	+5.022	<.001	.002	3	1
SKIN	C7orf77 →	+0.111	+4.415	<.001	.007	3	1
SKIN	FAM25C →	+0.766	+4.930	<.001	.001	3	1
LARGE_INTESTINE	CBLIF →	+0.283	+3.285	.001	.007	3	1
LARGE_INTESTINE	CEACAM20 →	+0.147	+4.022	<.001	.001	3	1
LARGE_INTESTINE	SMIM33 →	+0.453	+3.355	.005	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

MAGEB4 by ZNF212 expression — SKIN

Explore this box plot interactively →