ZNF208

Across TCGA patient cohorts, ZNF208 mutation is significantly associated with the RNA expression of many other genes, with 6,353 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF208-associated genes across cancer lineages are LSM3, KIF2C, and PDCD2L. Each is linked with ZNF208 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZNF208-to-partner and partner-to-ZNF208 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LSM3 grouped by ZNF208-low versus ZNF208-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF208→partner) and Y-score (partner→ZNF208) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LSM3 →	+0.479	+2.357	<.001	<.001	3	5
UCEC	KIF2C →	+0.538	+1.480	.001	<.001	3	5
UCEC	PDCD2L →	+0.322	+2.828	.001	<.001	3	5
UCEC	NDUFA6 →	+0.576	+2.595	<.001	<.001	3	5
STAD	SAC3D1 →	+0.457	+1.944	.007	.008	3	4
SKCM	DCAKD →	+0.256	+1.163	.003	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,353 associations by consensus.

LSM3 by ZNF208 expression — UCEC

Explore this box plot interactively →