ZNF208

Across TCGA pan-cancer cohorts, ZNF208 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated ZNF208 data layer compared with 8 for mutation status.

The strongest signal is observed in mesothelioma (MESO), where higher ZNF208 RNA is associated with better overall survival. In most high-consensus cancer types, elevated ZNF208 expression acts as an unfavorable survival marker, although some lineages such as MESO and UVM show a favorable association.

MESO, UVM, and BLCA are the cancer types where ZNF208 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Median	III,IV	0.516	0.269	<.001	127	view →
UVM	OS	Median	All	0.769	0.430	.001	72	view →
BLCA	OS	Tertile	IV	0.211	0.758	<.001	55	view →
LUAD	OS	Tertile	II,III,IV	0.674	0.475	.005	45	view →
THCA	DFS	Tertile	All	0.968	0.643	<.001	37	view →
UCS	DFS	Median	II,III,IV	0.530	0.190	.006	32	view →
BRCA	DFS	Tertile	III,IV	0.871	0.734	.009	28	view →
LUSC	DFS	Quartile	II,III,IV	0.264	0.459	.011	18	view →
ACC	OS	Median	III,IV	0.808	0.421	.012	17	view →
KIRP	DFS	Median	All	0.981	0.770	.002	17	view →
ESCA	DFS	Tertile	III,IV	0.589	0.258	.014	16	view →
CESC	DFS	Quartile	All	0.737	0.858	.013	16	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

ZNF208–MESO (OS)

Open the MESO breakdown →