Across TCGA cell cohorts, ZNF197 mutation is significantly associated with the RNA expression of many other genes, with 31 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF197-associated genes across cancer lineages are CLRN1, SLC5A8, and CHIA. Each is linked with ZNF197 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF197-to-partner and partner-to-ZNF197 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF197→partner) and Y-score (partner→ZNF197) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	CLRN1 →	+0.020	+4.681	<.001	.003	3	2
OESOPHAGUS	SLC5A8 →	+0.070	+4.906	<.001	.006	3	1
URINARY_TRACT	CHIA →	+1.476	+5.087	<.001	.004	3	1
SKIN	OR6B3 →	+0.136	+6.022	<.001	.001	3	1
LUNG_SCLC	SMR3A →	+0.193	+5.643	<.001	.002	3	1
LUNG_SCLC	PYDC2 →	+0.203	+5.643	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

Exploration

ZNF197 survival (RNA) · tumor vs normal (RNA) · all ZNF197 data types