ZNF141

Across TCGA patient cohorts, ZNF141 mutation is significantly associated with the RNA expression of many other genes, with 712 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF141-associated genes across cancer lineages are PTMAP6, RNU6-908P, and RPS12P15. Each is linked with ZNF141 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF141-to-partner and partner-to-ZNF141 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PTMAP6 grouped by ZNF141-low versus ZNF141-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF141→partner) and Y-score (partner→ZNF141) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	PTMAP6 →	+0.287	+4.241	<.001	.003	3	3
BLCA	RNU6-908P →	+0.511	+4.680	<.001	.003	3	2
COAD	RPS12P15 →	+0.209	+5.278	<.001	<.001	3	2
UCEC	IGHD2-2 →	+1.124	+1.787	.001	.006	3	2
UCEC	RN7SKP286 →	+0.038	+3.812	<.001	.008	3	2
COAD	MIR147A →	+0.486	+4.308	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 712 associations by consensus.

PTMAP6 by ZNF141 expression — LUAD

Explore this box plot interactively →