ZNF141

Across TCGA cell cohorts, ZNF141 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,372 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ZNF141-associated GO terms across cancer lineages are Regulation of transcription initiation by RNA polymerase II, Nucleic acid catabolic process, and Co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway. Each is linked with ZNF141 in more than 13 cancer types. Because this analysis shows association rather than direction, both ZNF141-to-partner and partner-to-ZNF141 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of transcription initiation by RNA polymerase II grouped by ZNF141-low versus ZNF141-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF141→partner) and Y-score (partner→ZNF141) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of transcription initiation by RNA polymerase II →	+0.065	+1.823	.001	<.001	3	14
BONE	Nucleic acid catabolic process →	+0.057	+1.033	<.001	.008	3	14
UPPER_AERODIGESTIVE_TRACT	Co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway →	+0.129	+1.318	<.001	<.001	3	14
PANCREAS	mRNA export from nucleus →	+0.107	+1.000	<.001	<.001	3	14
BONE	Regulation of DNA recombination →	+0.096	+1.130	<.001	<.001	3	13
OESOPHAGUS	Regulation of DNA-templated transcription initiation →	+0.068	+1.596	.003	.005	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,372 associations by consensus.

Regulation of transcription initiation by RNA polymerase II by ZNF141 expression — OESOPHAGUS

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