ZNF141

Across TCGA cell cohorts, ZNF141 mutation is significantly associated with the RNA expression of many other genes, with 43 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ZNF141-associated genes across cancer lineages are OR6V1, TTLL2, and LAIR2. Each is linked with ZNF141 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF141-to-partner and partner-to-ZNF141 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR6V1 grouped by ZNF141-low versus ZNF141-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF141→partner) and Y-score (partner→ZNF141) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	OR6V1 →	+0.014	+3.584	<.001	.001	3	2
BLOOD_Leukemia	TTLL2 →	+0.259	+4.000	.005	.001	3	2
BONE	LAIR2 →	+0.043	+5.169	<.001	.004	3	1
BONE	LIPK →	+0.023	+5.169	<.001	.004	3	1
BONE	KRTAP22-2 →	+0.290	+5.169	<.001	.004	3	1
BONE	TAS2R41 →	+0.023	+5.169	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 43 associations by consensus.

OR6V1 by ZNF141 expression — PANCREAS

Explore this box plot interactively →