ZNF114

Across TCGA patient cohorts, ZNF114 protein abundance is significantly associated with the RNA expression of many other genes, with 1,974 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF114-associated genes across cancer lineages are CD52, H4C1, and EIF4BP3. Each is linked with ZNF114 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF114-to-partner and partner-to-ZNF114 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF114 versus CD52 in GBM, with a Pearson correlation of -0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF114→partner) and Y-score (partner→ZNF114) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CD52 →	-1.027	-1.035	<.001	.002	3	2
GBM	H4C1 →	+1.199	+1.101	<.001	<.001	3	2
HNSC	EIF4BP3 →	-1.473	-2.310	<.001	.003	2	2
LUAD	ST3GAL5 →	-1.320	-1.357	.003	.001	3	1
LUAD	RPS26P55 →	-0.330	-1.295	.003	.005	3	1
LUAD	MYL12AP1 →	+0.517	+1.173	.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,974 associations by consensus.

ZNF114 vs CD52 — GBM

Explore this scatter interactively →