ZNF114

Across TCGA cell cohorts, ZNF114 protein abundance is significantly associated with the go_rna of many other GO terms, with 2,739 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible ZNF114-associated GO terms across cancer lineages are Termination of RNA polymerase I transcription, Modulation by symbiont of entry into host, and Adenylate cyclase-activating serotonin receptor signaling pathway. Each is linked with ZNF114 in more than 6 cancer types. Because this analysis shows association rather than direction, both ZNF114-to-partner and partner-to-ZNF114 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Termination of RNA polymerase I transcription grouped by ZNF114-low versus ZNF114-high in PANCREAS.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF114→partner) and Y-score (partner→ZNF114) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Termination of RNA polymerase I transcription →	-0.144	-0.806	<.001	<.001	3	6
BREAST	Modulation by symbiont of entry into host →	-0.086	-0.718	<.001	.001	3	6
OVARY	Adenylate cyclase-activating serotonin receptor signaling pathway →	+0.129	+0.587	.006	.004	2	7
PANCREAS	Sperm motility →	-0.099	-0.835	<.001	<.001	3	6
LARGE_INTESTINE	Regulation of endocytosis →	-0.040	-0.782	.001	.007	3	6
LARGE_INTESTINE	Smooth muscle contraction →	-0.109	-1.033	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,739 associations by consensus.

Termination of RNA polymerase I transcription by ZNF114 expression — PANCREAS

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