ZMYND8

Across TCGA cell cohorts, ZMYND8 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,379 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ZMYND8-associated GO terms across cancer lineages are Regulation of dendritic spine maintenance, Positive regulation of dendritic spine maintenance, and Viral translational termination-reinitiation. Each is linked with ZMYND8 in more than 11 cancer types. Because this analysis shows association rather than direction, both ZMYND8-to-partner and partner-to-ZMYND8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of dendritic spine maintenance grouped by ZMYND8-low versus ZMYND8-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZMYND8→partner) and Y-score (partner→ZMYND8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Regulation of dendritic spine maintenance →	+0.204	+1.025	<.001	.004	3	12
OVARY	Positive regulation of dendritic spine maintenance →	+0.674	+1.089	.004	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Viral translational termination-reinitiation →	+0.109	+1.125	<.001	<.001	3	11
BONE	Late viral transcription →	+0.126	+0.860	<.001	.002	3	10
UPPER_AERODIGESTIVE_TRACT	Negative regulation of DNA metabolic process →	+0.052	+0.880	.002	.002	3	10
LUNG_NSCLC_LUAD	Regulation of androgen receptor signaling pathway →	+0.059	+0.976	.001	<.001	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,379 associations by consensus.

Regulation of dendritic spine maintenance by ZMYND8 expression — KIDNEY

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