ZMYM2

Across TCGA patient cohorts, ZMYM2 mutation is significantly associated with the RNA expression of many other genes, with 5,165 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZMYM2-associated genes across cancer lineages are ZNHIT3, HAUS1, and MRPL16. Each is linked with ZMYM2 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZMYM2-to-partner and partner-to-ZMYM2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZNHIT3 grouped by ZMYM2-low versus ZMYM2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZMYM2→partner) and Y-score (partner→ZMYM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ZNHIT3 →	+0.375	+2.243	<.001	<.001	3	3
UCEC	HAUS1 →	+0.482	+2.223	<.001	<.001	3	3
UCEC	MRPL16 →	+0.272	+2.267	<.001	<.001	3	3
UCEC	RCC1 →	+0.454	+1.412	<.001	<.001	3	3
UCEC	TPI1 →	+0.404	+2.035	<.001	<.001	3	3
LUAD	SNRPGP7 →	+0.221	+4.303	<.001	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,165 associations by consensus.

ZNHIT3 by ZMYM2 expression — UCEC

Explore this box plot interactively →