ZIM3

Across TCGA cell cohorts, ZIM3 RNA expression is significantly associated with the mutation status of many other genes, with 41 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ZIM3-associated genes across cancer lineages are N4BP2, ACTR1B, and DSTYK. Each is linked with ZIM3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZIM3-to-partner and partner-to-ZIM3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, N4BP2 grouped by ZIM3-low versus ZIM3-high in LUNG_NSCLC_LUSC.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZIM3→partner) and Y-score (partner→ZIM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	N4BP2 →	+4.643	+0.043	.008	<.001	3	2
PANCREAS	ACTR1B →	+4.614	+0.005	.004	<.001	3	1
PANCREAS	DSTYK →	+4.614	+0.005	.004	<.001	3	1
PANCREAS	ZNF226 →	+4.614	+0.005	.004	<.001	3	1
PANCREAS	NBPF14 →	+4.029	+0.004	.007	<.001	3	1
LUNG_NSCLC_LUSC	WSCD1 →	+4.643	+0.043	.008	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

N4BP2 by ZIM3 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →