ZFYVE28

Across TCGA cell cohorts, ZFYVE28 mutation is significantly associated with the RNA expression of many other genes, with 69 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZFYVE28-associated genes across cancer lineages are CCDC179, NR4A2, and RCHY1. Each is linked with ZFYVE28 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZFYVE28-to-partner and partner-to-ZFYVE28 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCDC179 grouped by ZFYVE28-low versus ZFYVE28-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFYVE28→partner) and Y-score (partner→ZFYVE28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	CCDC179 →	+0.030	+4.614	<.001	.004	3	1
LARGE_INTESTINE	NR4A2 →	+0.780	+3.212	.004	.006	3	1
LARGE_INTESTINE	RCHY1 →	+0.761	+3.212	.003	.006	3	1
LARGE_INTESTINE	STOML2 →	+0.480	+3.299	.002	.004	3	1
LARGE_INTESTINE	HSFY2 →	+0.007	+2.754	.001	.009	3	1
LARGE_INTESTINE	ZNF566 →	+0.636	+3.299	.004	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 69 associations by consensus.

CCDC179 by ZFYVE28 expression — PANCREAS

Explore this box plot interactively →