ZFYVE27

Across TCGA patient cohorts, ZFYVE27 mutation is significantly associated with the RNA expression of many other genes, with 3,080 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZFYVE27-associated genes across cancer lineages are COPS8P1, RNU6-502P, and SNORD62A. Each is linked with ZFYVE27 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZFYVE27-to-partner and partner-to-ZFYVE27 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, COPS8P1 grouped by ZFYVE27-low versus ZFYVE27-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFYVE27→partner) and Y-score (partner→ZFYVE27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	COPS8P1 →	+0.101	+2.289	<.001	.004	3	2
BLCA	RNU6-502P →	+0.449	+5.588	<.001	.004	3	2
UCEC	SNORD62A →	+0.494	+2.163	<.001	.002	3	2
UCEC	RNA5SP419 →	+1.059	+3.246	<.001	<.001	3	2
UCEC	RNA5SP413 →	+1.406	+2.447	<.001	<.001	3	2
LIHC	PRAMEF5 →	+0.113	+5.758	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,080 associations by consensus.

COPS8P1 by ZFYVE27 expression — UCEC

Explore this box plot interactively →