ZDHHC21

Across TCGA patient cohorts, ZDHHC21 protein abundance is significantly associated with the RNA expression of many other genes, with 2,682 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible ZDHHC21-associated genes across cancer lineages are CDCA4P1, FUBP3, and VDR. Each is linked with ZDHHC21 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZDHHC21-to-partner and partner-to-ZDHHC21 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZDHHC21 versus CDCA4P1 in LUAD, with a Pearson correlation of 0.57.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZDHHC21→partner) and Y-score (partner→ZDHHC21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CDCA4P1 →	+0.851	+0.615	<.001	<.001	3	3
LUAD	FUBP3 →	+0.229	+0.609	.004	<.001	3	2
CCRCC	VDR →	+0.857	+0.484	.002	.008	3	2
BRCA	HSD11B1 →	-0.950	-0.649	.003	.001	3	2
HNSC	BSPRY →	+0.903	+0.355	.002	.001	3	2
HNSC	RAB25 →	+0.903	+0.434	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,682 associations by consensus.

ZDHHC21 vs CDCA4P1 — LUAD

Explore this scatter interactively →