ZDHHC21

Across TCGA patient cohorts, ZDHHC21 mutation is significantly associated with the RNA expression of many other genes, with 2,608 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZDHHC21-associated genes across cancer lineages are RN7SL134P, NPAP1P2, and RNA5SP57. Each is linked with ZDHHC21 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZDHHC21-to-partner and partner-to-ZDHHC21 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL134P grouped by ZDHHC21-low versus ZDHHC21-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZDHHC21→partner) and Y-score (partner→ZDHHC21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL134P →	+0.141	+2.484	<.001	.001	3	2
UCEC	NPAP1P2 →	+0.029	+2.171	<.001	.005	3	2
SKCM	RNA5SP57 →	+0.428	+6.328	<.001	.001	3	2
COAD	MIR1283-1 →	+0.726	+7.741	<.001	.009	3	2
UCEC	YTHDF3-AS1 →	+0.555	+1.960	.003	.009	3	1
UCEC	HSPE1-MOB4 →	+0.143	+1.951	.002	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,608 associations by consensus.

RN7SL134P by ZDHHC21 expression — UCEC

Explore this box plot interactively →