ZDHHC15

Across TCGA patient cohorts, ZDHHC15 mutation is significantly associated with the RNA expression of many other genes, with 2,101 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZDHHC15-associated genes across cancer lineages are RN7SKP181, RNA5SP411, and OR2B7P. Each is linked with ZDHHC15 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZDHHC15-to-partner and partner-to-ZDHHC15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP181 grouped by ZDHHC15-low versus ZDHHC15-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZDHHC15→partner) and Y-score (partner→ZDHHC15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RN7SKP181 →	+0.368	+4.239	<.001	.005	3	4
LUSC	RNA5SP411 →	+0.303	+4.412	.006	.006	3	3
COAD	OR2B7P →	+0.372	+3.036	<.001	.003	3	3
COAD	RPL7P55 →	+0.199	+3.278	<.001	.005	3	3
BRCA	MIR7159 →	+0.616	+5.317	<.001	.006	3	2
BLCA	LINGO1-AS2 →	+0.060	+6.444	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,101 associations by consensus.

RN7SKP181 by ZDHHC15 expression — COAD

Explore this box plot interactively →