ZC3H18

Across TCGA patient cohorts, ZC3H18 protein abundance is significantly associated with the RNA expression of many other genes, with 12,680 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZC3H18-associated genes across cancer lineages are TMEM147-AS1, RFWD3, and SF3B3. Each is linked with ZC3H18 in more than 5 cancer types. Because this analysis shows association rather than direction, both ZC3H18-to-partner and partner-to-ZC3H18 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZC3H18 versus TMEM147-AS1 in LSCC, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZC3H18→partner) and Y-score (partner→ZC3H18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TMEM147-AS1 →	+0.589	+0.223	<.001	<.001	3	6
LSCC	RFWD3 →	+0.661	+0.230	<.001	<.001	3	6
UCEC	SF3B3 →	+0.676	+0.209	<.001	<.001	3	6
BRCA	AFG3L1P →	+0.454	+0.278	<.001	<.001	3	6
UCEC	PRMT7 →	+0.619	+0.165	<.001	<.001	3	6
HNSC	MSH2 →	+0.617	+0.202	.002	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,680 associations by consensus.

ZC3H18 vs TMEM147-AS1 — LSCC

Explore this scatter interactively →