ZC3H13

Across TCGA patient cohorts, ZC3H13 mutation is significantly associated with the RNA expression of many other genes, with 6,073 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZC3H13-associated genes across cancer lineages are ATAD3B, BTBD6, and C15orf61. Each is linked with ZC3H13 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZC3H13-to-partner and partner-to-ZC3H13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATAD3B grouped by ZC3H13-low versus ZC3H13-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZC3H13→partner) and Y-score (partner→ZC3H13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATAD3B →	+0.297	+1.657	.004	.001	3	4
COAD	BTBD6 →	+0.454	+4.141	<.001	<.001	3	3
UCEC	C15orf61 →	+0.388	+2.090	<.001	<.001	3	3
UCEC	HMBS →	+0.413	+1.584	<.001	<.001	3	3
UCEC	SENP3-EIF4A1 →	+0.083	+1.906	<.001	.001	3	3
UCEC	CIRBP-AS1 →	+0.517	+1.450	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,073 associations by consensus.

ATAD3B by ZC3H13 expression — UCEC

Explore this box plot interactively →