chromosome 15 open reading frame 61Genealiases: []
Q-omics provides the consensus-scored C15orf61 profile across patient tissues and cancer cell-line models. C15orf61 expression is associated with patient survival in 19 of 34 cancer types, with the highest sampling consensus in KICH. Among the 18 cancer types available for tumor–normal comparison, C15orf61 is differentially expressed in 14, with the highest sampling consensus in THCA. Additionally, C15orf61 RNA expression shows 19,300 significant gene co-expression associations, with the highest sampling consensus in ACC. Together, these results highlight KICH, THCA, and ACC as cancer lineages where C15orf61 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for C15orf61 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes C15orf61 survival associations across molecular data types. C15orf61 RNA expression shows survival associations in the most cancer types (19). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible C15orf61 RNA expression–survival associations across cancer types. High C15orf61 expression shows unfavorable associations in KICH, KIRP, ACC and UVM, but favorable associations in KIRC and LUSC. The KICH Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .004). Together, the overview and detailed table identify KICH as the clearest survival context for C15orf61 RNA expression.
This table summarizes C15orf61 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 14. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for C15orf61. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. C15orf61 shows lower tumor expression in THCA, KIRP and LUAD and higher tumor expression in COAD, LIHC and BLCA. The THCA box plot shows higher C15orf61 RNA expression in normal versus tumor tissue (log2 FC = −1.320, t-test p < 0.001).
This table shows molecular features associated with C15orf61 in patient tissues and cancer cell lines. In patient samples, C15orf61 shows the broadest associations at the RNA and protein expression levels, with ACC recurring as the lineage with the largest associated feature set. In cancer cell lines, C15orf61 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in KIDNEY, while CRISPR and shRNA rows add functional-dependency signals in STOMACH and BLOOD_Lymphoma.
