ZC3H12D

Across TCGA patient cohorts, ZC3H12D protein abundance is significantly associated with the RNA expression of many other genes, with 12,509 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZC3H12D-associated genes across cancer lineages are WDFY4, PIK3CG, and BTK. Each is linked with ZC3H12D in more than 5 cancer types. Because this analysis shows association rather than direction, both ZC3H12D-to-partner and partner-to-ZC3H12D results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZC3H12D versus WDFY4 in GBM, with a Pearson correlation of 0.66.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZC3H12D→partner) and Y-score (partner→ZC3H12D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	WDFY4 →	+1.081	+0.671	<.001	<.001	3	6
HNSC	PIK3CG →	+1.004	+0.703	.002	.002	3	5
HNSC	BTK →	+0.978	+0.629	<.001	.002	3	5
GBM	VNN2 →	+1.256	+0.780	<.001	<.001	3	5
GBM	FAM78A →	+1.224	+0.880	<.001	<.001	3	5
HNSC	IL2RG →	+1.520	+0.871	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,509 associations by consensus.

ZC3H12D vs WDFY4 — GBM

Explore this scatter interactively →