ZC3H12A

Across TCGA patient cohorts, ZC3H12A RNA expression is significantly associated with the protein abundance of many other proteins, with 16,850 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZC3H12A-associated proteins across cancer lineages are LCN2, ELANE, and MPO. Each is linked with ZC3H12A in more than 8 cancer types. Because this analysis shows association rather than direction, both ZC3H12A-to-partner and partner-to-ZC3H12A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZC3H12A versus LCN2 in GBM, with a Pearson correlation of 0.68.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZC3H12A→partner) and Y-score (partner→ZC3H12A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	LCN2 →	+1.323	+0.896	<.001	<.001	3	9
GBM	ELANE →	+0.834	+0.848	<.001	<.001	3	6
GBM	MPO →	+1.126	+0.880	<.001	<.001	3	6
GBM	MNDA →	+1.011	+0.963	<.001	<.001	3	6
COAD	S100A9 →	+1.525	+0.876	<.001	<.001	3	6
LSCC	S100A12 →	+1.440	+1.068	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,850 associations by consensus.

ZC3H12A vs LCN2 — GBM

Explore this scatter interactively →